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AKILLI SİSTEMLER VE UYGULAMALARI DERGİSİ
JOURNAL OF INTELLIGENT SYSTEMS WITH APPLICATIONS
J. Intell. Syst. Appl.
E-ISSN: 2667-6893
Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License.

Gender Effects On Prefrontal Cortex Oxygenation Levels During Auditory Oddball Task In Children

Çocuklarda İşitsel Oddball Paradigması Esnasında Prefrontal Korteks Oksijenlenmesinde Cinsiyetin Etkileri

How to cite: Altınkaynak M, Güven A, Dolu N, İzzetoğlu M, Pektaş F, Özmen S, Demirci E. Gender effects on prefrontal cortex oxygenation levels during auditory oddball task in children. Akıllı Sistemler ve Uygulamaları Dergisi (Journal of Intelligent Systems with Applications) 2018; 1(1): 1-7. DOI: 10.54856/jiswa.201805049

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Title: Gender Effects On Prefrontal Cortex Oxygenation Levels During Auditory Oddball Task In Children

Abstract: In this study, our aim was to investigate gender effects on prefrontal cortex oxygenation. Auditory oddball paradigm used as cognitive task. Prefrontal cortex oxygenation is assessed by monitoring changes in blood oxygenation using functional nearinfrared spectroscopy (fNIRS). The fNIRS were recorded during the 'oddball' paradigm in which two stimuli (target and standard) were presented in random order. Subjects were asked to press a button in response to the target stimulus. 12 male healthy children and 9 female healthy children were included the study. As a result; it is observed that the males exhibited higher prefrontal activation during auditory oddball task than females. This results suggest that gender had an effect on prefrontal cortex oxygenation therefore gender matching is important for studies of brain function using fNIRS.

Keywords: uditory oddball paradigm; gender difference; functional near infrared spectroscopy


Başlık: Çocuklarda İşitsel Oddball Paradigması Esnasında Prefrontal Korteks Oksijenlenmesinde Cinsiyetin Etkileri

Özet: Bu çalışmada, prefrontal korteks oksijenlenmesinde cinsiyet etkileri araştırılmıştır. Bilişsel test olarak işitsel oddball paradigması uygulanmıştır. Prefrontal korteks oksijenlenmesi fonksiyonel yakın kızılötesi sprektroskopisi (fNIRS) kullanılarak kandaki oksijenlenmenin değişimine göre belirlenmiştir. fNIRS kayıtları iki uyaranın rastgele kullanıldığı (hedef ve standart) oddball paradigması ile alınmıştır. Deneklerden hedef sesleri duyduklarında butona basmaları istenmiştir. 12 sağlıklı erkek çocuk ve 9 sağlıklı kız çocuk çalışmaya dahil edilmiştir. Sonuç olarak; erkek katılımcıların işitsel oddball testi sırasında kız katılımcılardan daha fazla prefrontal aktivasyon gösterdiği gözlenmiştir. Bu sonuçlar cinsiyetin prefrontal kortex oksijenlenmesinde etkili olduğunu göstermektedir. Bu durum fNIRS kullanarak yapılan beyin fonksiyonu çalışmalarında cinsiyet eşleştirmenin önemli olduğunu göstermektedir.

Anahtar kelimeler: İşitsel oddball paradigması; cinsiyet etkisi; fonksiyonel yakın kızılötesi spektroskopisi


Bibliography:
  • Willis MW, Ketter TA, Kimbrell TA, George MS, Herscovitch P, Danielson AL, Benson BE, Post RM. Age, sex and laterality effects on cerebral glucose metabolism in healthy adults. Psychiatry Research: Neuroimaging 2002; 114(1): 23-37.
  • Marumo K, Takizawa R, Kawakubo Y, Onitsuka T, Kasai K. Gender difference in right lateral prefrontal hemodynamic response while viewing fearful faces: a multi-channel nearinfrared spectroscopy study. Neuroscience Research 2009; 63(2): 89-94.
  • Koch K, Pauly K, Kellermann T, Seiferth NY, Reske M, Backes V, Stocker T, Shah JN, Amunts K, Kircher T, Schneider F, Habel U. Gender differences in the cognitive control of emotion: An fMRI study. Neuropsychologia 2007; 45(12): 2744-2754.
  • Fujimoto T, Matsumoto T, Fujita S, Takeuchi K, Nakamura K, Mitsuyama Y, Kato N. Changes in glucose metabolism due to aging and gender-related differences in the healthy human brain. Psychiatry Research: Neuroimaging 2008; 164(1): 58-72.
  • Volkow ND, Wang GJ, Fowler JS, Hitzemann R, Pappas N, Pascani K, Wong C. Gender differences in cerebellar metabolism: test–retest reproducibility. The American Journal of Psychiatry 1997; 154: 119–121.
  • Speck O, Ernst T, Braun J, Koch C, Miller E, Chang L. Gender differences in the functional organization of the brain for working memory. Neuroreport 2000; 11(11): 2581-2585.
  • Bell EC, Willson MC, Wilman AH, Dave S, Silverstone PH. Males and females differ in brain activation during cognitive tasks. Neuroimage 2006; 30(2): 529-538.
  • Okamoto M, Matsunami M, Dan H, Kohata T, Kohyama K, Dan I. Prefrontal activity during taste encoding: An fNIRS study. Neuroimage 2006; 31(2): 796–806.
  • Izzetoglu M, Bunce SC, Izzetoglu K, Onaral B, Pourrezaei K. Functional brain imaging using near-infrared technology for cognitive activity assessment. IEEE Engineering in Medicine and Biology Magazine 2007; 26(4): 38–46.
  • Persson J, Herlitz A, Engman J, Morell A, Sjolie D, Wikstrom J, Soderlund H. Remembering our origin: Gender differences in spatial memory are reflected in gender differences in hippocampal lateralization. Behavioural Brain Research 2013; 256: 219-228.
  • Li T, Luo Q, Gong H. Genderspecific hemodynamics in prefrontal cortex during a verbal working memory task by nearinfrared spectroscopy. Behavioural Brain Research 2010; 209(1): 148-153.
  • Voyer D, Voyer S, Bryden MP. Magnitude of sex differences in spatial abilities: A meta-analysis and consideration of critical variables. Psychological Bulletin 1995; 117(2): 250-270.
  • Wechsler D. WISC-R Manuel for The Wechsler Intelligence Scale For Children Revised. New York: Psychological Corporation, 1972.
  • Cope M, Delpy DT. System for longterm measurement of cerebral blood flow and tissue oxygenation on newborn infants by infrared transillumination. Medical & Biological Engineering & Computing 1988; 26: 289–294.
  • Izzetoglu M, Izzetoglu K, Bunce S, Ayaz H, Devaraj A, Onaral B, Pourrezaei K. Functional near-infrared neuroimaging. IEEE Transactions on Neural Systems and Rehabilitation Engineering 2005; 13(2): 153-159.
  • Ehlis AC, Ringel TM, Plichta MM, Richter MM, Herrmann MJ, Fallgatter AJ. Cortical correlates of auditory sensory gating: A simultaneous near-infrared spectroscopy event-related potential study. Neuroscience 2009; 159: 1032–1043.
  • Kulynych JJ, Vladar K, Jones DW, Weinberger DR. Gender differences in the normal lateralization of the supratemporal cortex: MRI surface-rendering morphometry of heschl's gyrus and the planum temporale. Cerebral Cortex 1994; 4: 107–11.